ISSN No.
2395-3306
(Online)
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 Volume  3 / Issue 2 / June 2016   (pp 1-23)
Green Chemistry: The Atom Economy Pradip K. Jenaa*, Susanta K. Sahub and A. Samantaraya
Int. J. Chem. Pharm. Rev. Res., 2016, 3(2), pp 1-6  •  Abstract  •  Fulltext    •   Citations: 0    •   Article Views: 0
Green Chemistry can be defined as the practice of chemical science and manufacturing in a manner that is sustainable, safe and non-polluting, which consumes minimum amount of materials and energy that producing little or no waste material. It usually deals with increasing profits and promoting innovation while protecting human health and the environment. Basically green chemistry garnishes a vast body of chemical knowledge and applies it to the production, use and ultimate dispose of chemicals in a way that minimizes consumption of materials, exposure of living organisms (including humans) to toxic substances and damage to the environment. The success of it depends on the training and education of a new generation of Chemists. Industrialists, Scientists, Researchers and Students at all levels to introduce the philosophy and practice of green chemistry.

Momordica Charantia L Extract Ameliorates Oxidative Damage in Normal Human Erythrocyte Membrane V. Kalpana Devi1, R.Maheswari2,*
Int. J. Chem. Pharm. Rev. Res., 2016, 3(2), pp 7-17  •  Abstract  •  Fulltext    •   Citations: 0    •   Article Views: 0
In our present study, an attempt has been made to study the effect of AAPH on biochemical parameters and ameliorating effects of the fruit (vegetable) extract of Momordica charantia L (MC), Karela, (Bitter Melon) in human erythrocytes. The aim and purpose of our study was to evaluate the ability of both the ethanol (EtOH) and ethylacetate/ethanol (EA/EtOH) extracts from the whole fruit Momordica charantia L to protect normal human erythrocytes against oxidative damage in-vitro. Our study was determined that the oxidative hemolysis and lipid/protein peroxidation of erythrocytes induced by the aqueous peroxyl radical [2,2’-azobis (2-amidinopropane) dihydrochloride (AAPH)] were suppressed by both EtOH (50–150 µg/ml) and EA/EtOH (25–75 µg/ml) extracts of Momordica charantia L in concentration and time-dependent manners. Momordica charantia L extracts also prevented the decline of superoxide dismutase (SOD) activity and the depletion of cytosolic glutathione (GSH) and ATP in Erythrocytes. Our results imply that Momordica charantia L has the protective antioxidant properties. 

Evaluation of nature of Cyclization reaction of SM (2-(N-methyl-N-(1-phenylvinyl) carbamoyl)phenyl acetate) using computational methods Sujit Kumar Dehury* and P. G. R. Achary
Int. J. Chem. Pharm. Rev. Res., 2016, 3(2), pp 18-23  •  Abstract  •  Fulltext    •   Citations: 0    •   Article Views: 0
2-(N-methyl-N-(1-phenylvinyl)carbamoyl)phenyl acetate (SM) was taken to carry out the computational study for the cyclisation reaction. Basically, Semi empirical methods, Hartree Fock method and Density functional theory method have been utilized to know the nature of cyclisation reaction. The stability of the products has been evaluated along with dipole moment study for charge distribution. 
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